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Monday, October 5, 2026

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Nobel Prize · Monday, October 5, 2026

Nobel Prize in medicine goes to three scientists who found a light switch for brain cells

The File desk · Oct 5, 2026, 10:39 AM UTC

Status

Confirmed (Nobel Prize press release, Oct. 5, 2026)

Three scientists won this year’s Nobel Prize in Physiology or Medicine for optogenetics. The method lets researchers turn single nerve cells on or off with light inside a living brain. Peter Hegemann and Georg Nagel found the key protein, channelrhodopsin, in a one-celled pond alga. Karl Deisseroth turned it into a light-controlled switch for nerve cells, first in cells from rats in 2005 and then in living mice two years later.

The press release is dated Oct. 5, 2026. The official schedule said the prize would be announced Monday, Oct. 5, at 11:30 a.m. Central European Summer Time at the earliest, which is 5:30 a.m. Eastern. The release carries a date and no clock time.

Deisseroth, born 1971, is at the Howard Hughes Medical Institute and Stanford University. Hegemann, born 1954, is at Humboldt University of Berlin. The prize-winning work was done at the Max Planck Institute for Biochemistry in Martinsried. Nagel, born 1953, is at the University of Würzburg. His prize-winning work was done at the Max Planck Institute for Biophysics in Frankfurt. The three share 12 million Swedish kronor equally.

The citation is “for their discoveries concerning light-gated ion channels and optogenetics.” Hegemann and Nagel found that the algal protein opens a channel when blue light hits it, and that cells they put the protein into became sensitive to light. Deisseroth put the gene into nerve cells from rats and, with blue light, triggered a nerve signal. He published that in 2005. Two years later the switch worked in the brains of living mice.

Per Svenningsson, chair of the Nobel Committee for Physiology or Medicine, said: “Optogenetics provides opportunities for mapping the brain in a way that we could once only dream of.”

The release says researchers are using the method “in attempts to restore sight in people with visual impairment.” That is research. It is not an approved treatment.

What is still unknown or disputed

Primary sources

Every claim in this story is drawn from the documents below. If a fetch failed, that is recorded on the card.

  1. Source 1

    Press release: The Nobel Prize in Physiology or Medicine 2026

    Nobel Prize Outreach / Nobel Assembly at Karolinska Institutet · October 5, 2026

    Peter Hegemann and Georg Nagel discovered a remarkable protein, channelrhodopsin, in a single-celled alga. Karl Deisseroth transformed the protein into a light-controlled switch for nerve cells. Prize amount: 12 million Swedish kronor, to be shared equally between the laureates. “Optogenetics provides opportunities for mapping the brain in a way that we could once only dream of,” says Per Svenningsson. Researchers are using the method “in attempts to restore sight in people with visual impairment.”

    https://www.nobelprize.org/prizes/medicine/2026/press-release/

  2. Source 2

    All Nobel Prizes 2026

    NobelPrize.org · October 5, 2026

    Karl Deisseroth “for their discoveries concerning light-gated ion channels and optogenetics.”

    https://www.nobelprize.org/all-nobel-prizes-2026/

  3. Source 3

    Prize announcement dates

    NobelPrize.org · October 5, 2026

    The prize will be announced on Monday, 5 October, 11:30 CEST at the earliest, at the Nobel Assembly at Karolinska Institutet.

    https://www.nobelprize.org/prizes/about/prize-announcement-dates/