Week 2 · Friday, September 18, 2026
Bills beat Lions 41–31; full Week 2 slate ahead
The File desk · Sep 18, 2026, 2:08 PM UTC
Status
Confirmed (NFL.com Week 2 schedule payload and schedules hub, checked Sept. 18, 2026)
Buffalo beat Detroit 41–31 on Thursday night to open Week 2 of the National Football League season. NFL.com lists the Bills at 2–0 and the Lions at 1–1 after the game. The rest of Week 2: thirteen Sunday games on Sept. 20 (eight at 1:00 p.m. Eastern, two at 4:05, three at 4:25), Sunday Night Football with Indianapolis at Kansas City at 8:20 p.m. on NBC, and Monday Night Football with the New York Giants at the Los Angeles Rams on Sept. 21 at 8:15 p.m. on ESPN. No odds. No picks.
Buffalo beat Detroit 41–31 on Thursday night to open Week 2 of the National Football League season.
NFL.com lists the Bills at 2–0 and the Lions at 1–1 after the game.
Sunday, Sept. 20, at 1:00 p.m. Eastern: Carolina at Atlanta (FOX); New Orleans at Baltimore (CBS); Minnesota at Chicago (FOX); Cincinnati at Houston (CBS); Pittsburgh at New England (CBS); Green Bay at the New York Jets (FOX); Cleveland at Tampa Bay (CBS); Philadelphia at Tennessee (FOX).
At 4:05 p.m. Eastern: Jacksonville at Denver (CBS); Las Vegas at the Los Angeles Chargers (CBS).
At 4:25 p.m. Eastern: Seattle at Arizona (FOX); Washington at Dallas (FOX); Miami at San Francisco (FOX).
Sunday Night Football is Indianapolis at Kansas City at 8:20 p.m. on NBC.
Monday Night Football is the New York Giants at the Los Angeles Rams on Sept. 21 at 8:15 p.m. on ESPN.
No odds. No picks.
What is still unknown or disputed
- Local TV overlays for Sunday regional windows can vary by market.
Primary sources
Every claim in this story is drawn from the documents below. If a fetch failed, that is recorded on the card.
Source 1
NFL schedules hub (Week 2 / TNF final)
NFL.com · checked 2026-09-18
Lions 31, Bills 41, FINAL, Thursday, September 17th; Giants at Rams, Monday, September 21st, 8:15 PM, ESPN.
https://www.nfl.com/schedules
Source 2
NFL 2026 Regular Season Week 2 by-week schedule
NFL.com · checked 2026-09-18
Embedded weekly game details for REG week 2 with ISO kickoffs for all 16 games.
https://www.nfl.com/schedules/2026/by-week/week-2
Source 3
NFL How to Watch Week 2
NFL.com · checked 2026-09-18
TV network labels for Week 2 windows (FOX/CBS/NBC/Prime Video/ESPN). Note: that article’s Sunday/Monday calendar dates were wrong (said Sept 13/14); dates above follow the week-2 schedule JSON (Sept 20/21).
https://www.nfl.com/news/nfl-how-to-watch-week-2-schedule-key-matchups-and-more-x4041